The communication port configuration process is now almost automated. If using a USB reader (which has been standard with eTemperature since 2006) then don't change the com port.
Setting the com port to -1 will hide the "Reader not found" message. If eTemperature is only being used to display previously saved results then consider setting it to -1.
The TC-Spy uses a serial port. See TC-Spy for more information.